ABSTRACT
Objective To investigate the clinical efficacy of penetrating moxibustion plus short joint needling in treating restless leg syndrome (RLS).Methods Ninety RLS patients were randomized to treatment and control groups,45 cases each.The treatment group received penetrating moxibustion plus short joint needling and the control group,conventional medication (vitamin B tablets,vitamin B12 tablets and alprazolam tablets).The Restless Leg Syndrome Rating Scale (RLSRS) score and the Pittsburgh Sleep Quality Index (PSQI) score were recorded in the two groups before and after 30 days of treatment.The clinical therapeutic effects were compared between the groups.Results There were statistically significant pre-/post-treatment differences in the RLSRS and PSQI scores in both groups (P＜0.05).There were statistically significant post-treatment differences in the RLSRS and PSQI scores between the treatment and control groups (P＜0.05).The total efficacy rate was 95.6％ in the treatment group and 42.2％ in the control group;there was a statistically significant difference between the two groups (P＜0.05).Conclusion Penetrating moxibustion plus short joint needling is an effective way to treat RLS.
ABSTRACT
<p><b>OBJECTIVE</b>To explore the relevant factor of cannulated compression screws in treating femoral neck fractures.</p><p><b>METHODS</b>From January 2004 to January 2011, 190 patients with femoral neck fractures treated by cannulated compression screws were analyzed retrospectively. In all of the 190 cases, there were 104 males and 86 females with an average of 65 years (ranged, 21 to 83 years). According to Garden classification system, 25 cases were type I, 51 cases were type II, 58 cases were type II and 56 cases were type IV. The time from injury to operation was 15 h to 10 d (mean 3.5 d). The gender,age, trauma type, fracture type, osteoporosis, emergency operation, fracture reduction, relation between open reduction and nonunion were observed and analyzed.</p><p><b>RESULTS</b>All patients were followed-up for 12 to 84 months, with a mean of 38 months. All incisions obtained stage I healing. There were 23 patients with bone nonunion. The rate of nonunion was 12.1%. Single factor analysis showed that there were significant differences in age, trauma type, fracture type, fracture reduction and osteoporosis (P<0.05), but no meaning in gender, emergency operation, relation between open reduction and nonunion (P>0.05).</p><p><b>CONCLUSION</b>Cannulated compression screws for femoral neck fractures can obtain good outcomes, and age, trauma type, fracture type, fracture reduction and osteoporosis are main factors.</p>
Subject(s)
Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Young Adult , Bone Screws , Femoral Neck Fractures , Diagnostic Imaging , General Surgery , Follow-Up Studies , Fracture Fixation, Internal , Tomography, X-Ray ComputedABSTRACT
The residual protein mixture (the content is 4%, approximately), called Salvia miltiorrhiza antigen, was extracted from the Salvia miltiorrhiza cruel materials by mimicking the alcohol-deposit extracts process. Both rabbits and guinea pigs sensitized by Salvia miltiorrhiza could produce specified antibodies. Large molecular antigenic impurities were extracted from the Danshen injection and Xiangdan injection using the centrifugal filtering method. The test results of active systemic anaphylaxis (ASA) and passive cutaneous anaphylaxis (PCA) in guinea pigs confirmed that the extracted antigenic impurities could induce the anaphylaxis reaction in the animals which were sensitized by the Salvia miltiorrhiza antigen. Using the specified antibody produced from rabbits which were sensitiyed by Salvia miltiorrhiza, ELISA test method was developed to test the residual Salvia miltiorrhiza antigenic materials contained in the parenteral Chinese traditional medicines. Calculated as residual protein, the linear range was 0.08-5.12 microg x mL(-1) (r2 = 0.9906), the detection limit and quantization limit are 0.08 microg x mL(-1) and 0.4 microg x mL(-1), respectively. 308 batches of parenteral Chinese traditional medicines containing water-soluable components of Salvia miltiorrhiza were tested, and the Salvia miltiorrhiza antigenic impurities were spotted in 35 (11.4%) batches of samples. The test results show that the extracting process currently used can not remove the Salvia miltiorrhiza antigenic impurities completely, and this may be one of the reasons for anaphylactic reaction in clinics. The proposed ELISA method can be used for improving the manufacture process and for routine quality control of drug products.